PD-L1/Nampt-IN-1

CAS: 3054043-85-2

Ref. TM-T212272

Produktinformation

• Name: PD-L1/Nampt-IN-1
• Marke: Targetmol
• Beschreibung: PD-L1/Nampt-IN-1 is an orally active inhibitor that targets both PD-L1 and NAMPT (nicotinamide phosphoribosyltransferase), with IC50 values of 63 nM and 582 nM, respectively. It exhibits cross-species affinity, with KD values of 52.6 nM for hPD-L1 and 49.1 nM for mPD-L1. This compound effectively suppresses tumor growth by activating the tumor immune microenvironment and is applicable in melanoma research.

Chemische Eigenschaften

• Molekulargewicht: 452.55
• Formel: C₂₈H₂₈N₄O₂
• Farbe/Form: Solid