Suramin Sodium Salt

CAS: 129-46-4

Ref. TM-T2160

Produktinformation

• Name: Suramin Sodium Salt
• Synonyme: BAY-205, Suramin hexasodium salt, NF-060
• CAS: 129-46-4

Beschreibung

Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and tumor growth factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial growth factor (VEGF)- and basic fibroblast growth factor (bFGF)-induced angiogenesis; retroviral reverse transcriptase; uncoupling of G-proteins from receptors; topoisomerases; cellular folate transport; and steroidogenesis.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 1429.15
• Formel: C₅₁H₃₄N₆Na₆O₂₃S₆
• Reinheit: 99.97%
• Farbe/Form: White