Nedaplatin

CAS: 95734-82-0

Ref. TM-T2410

Produktinformation

• Name: Nedaplatin
• Synonyme: NSC 375101D, (Glycolato-O,O')Diammineplatinum(Ii), (SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum, 254-S, Acetic acid, hydroxy-, platinum complex, Aqupla, Cis-Diammine(Glycolato)Platinum(Ii), Diammine(Glycolato)Platinum(Ii) Nedaplatin Nsc 375101D, NSC 375101, Nedaplait, O(Sup 2))- Diammine(Hydroxyacetato(2-)-O(Sup 1 (Sp-4-3)-Platinu (Glycolato-O,O')Diammineplatinum(Ii) 254-S Cis-, O(Sup2))-Diammine(Hydroxyacetato(2-)-O(Sup1(Sp-4-3)-Platinu, Platinum(2+) Azanide - Hydroxyacetic Acid (1:2:1), Platinum, diammine[(hydroxy-κO)acetato(2-)-κO]-, (SP-4-3)-, Platinum, diammine[2-(hydroxy-κO)acetato(2-)-κO]-, (SP-4-3)-, Platinum, diammine[hydroxyacetato(2-)-O¹,O²]-, (SP-4-3)-, S 254, diamino[(hydroxy-kappaO)acetato(2-)-kappaO]platinum
• CAS: 95734-82-0

Beschreibung

Nedaplatin (NSC-375101D) is a derivative of cisplatin and DNA damage agent for tumor colony forming units (IC50: 94 μM). Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucleophilic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 303.17
• Formel: C₂H₈N₂O₃Pt
• Reinheit: 100%
• Farbe/Form: Straw Yellow Powder