IMM-01

CAS: 218795-74-5

Ref. TM-T25529

Produktinformation

• Name: IMM-01
• Synonyme: IMM01, IMM 01
• CAS: 218795-74-5

Beschreibung

IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin filaments, and their organization with microfilaments to establish and maintain cell polarity during migration and asymmetric division. GTP-bound Rho activates mDia family members by disrupting the interaction between the DID and DAD autoregulatory domains, which releases the FH2 domain to modulate actin and microtubule dynamics[1].

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 267.35
• Formel: C₁₂H₁₇N₃O₂S
• Reinheit: 98.81%
• Farbe/Form: Solid