Tenofovir exalidex

CAS: 911208-73-6

Ref. TM-T28946

Produktinformation

• Name: Tenofovir exalidex
• Synonyme: Tenofovir, HDP-Tenofovir, CMX-157, CMX157, CMX 157
• CAS: 911208-73-6

Beschreibung

Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant HIV strains, including those resistant to multiple nucleoside/nucleotide analogs. It effectively inhibits all major HIV-1 and HIV-2 subtypes in fresh human PBMCs, as well as all evaluated HIV-1 strains in monocyte-derived macrophages, displaying EC50 values between 0.2 and 7.2 nM. Oral administration of CMX157 shows no apparent toxicity. Additionally, Tenofovir exalidex exhibits antiviral properties against HBV.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 569.72
• Formel: C₂₈H₅₂N₅O₅P
• Reinheit: 99.54%
• Farbe/Form: Solid