Pyridone 6

CAS: 457081-03-7

Ref. TM-T3080

Produktinformation

• Name: Pyridone 6
• Synonyme: Janus-Associated Kinase Inhibitor I, JAK Inhibitor I, JAK I inhibitor, CMP 6
• Marke: Targetmol
• Beschreibung: Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).

Chemische Eigenschaften

• Molekulargewicht: 309.34
• Formel: C₁₈H₁₆FN₃O
• Reinheit: 97.1% - 98.74%
• Farbe/Form: Solid
• InChl: InChI=1S/C18H16FN3O/c1-18(2,3)17-21-14-10-5-4-9(19)8-12(10)13-11(15(14)22-17)6-7-20-16(13)23/h4-8H,1-3H3,(H,20,23)(H,21,22)
• InChI Key: InChIKey=VNDWQCSOSCCWIP-UHFFFAOYSA-N
• SMILES: CC(C)(C)c1nc2c3cc[nH]c(=O)c3c3cc(F)ccc3c2[nH]1