Lys05

CAS: 1391426-24-6

Ref. TM-T3437

Produktinformation

• Name: Lys05
• Synonyme: Lys01 trihydrochloride
• CAS: 1391426-24-6

Beschreibung

Lys05, or Lys01 trihydrochloride, is a potent, water soluble lysosomal autophagy inhibitor. Lys05 is a previously undescribed dimeric chloroquine which more potently accumulates in the lysosome and blocks autophagy compared with HCQ. Lys05 produced more potent antitumor activity as a single agent both in vitro and in vivo in multiple human cancer cell lines and xenograft models compared with HCQ. Lys05 is therefore a new lysosomal autophagy inhibitor that has potential to be developed further into a drug for cancer and other medical applications.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 549.75
• Formel: C₂₃H₂₆Cl₅N₅
• Reinheit: 99.23%
• Farbe/Form: Solid