X-376

CAS: 1365267-27-1

Ref. TM-T3550

Produktinformation

• Name: X-376
• Synonyme: Ensartinib, X-396
• CAS: 1365267-27-1

Beschreibung

X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins, and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 547.41
• Formel: C₂₅H₂₅Cl₂FN₆O₃
• Reinheit: 98.72%
• Farbe/Form: Solid