2-deoxy-D-Glucose-13C6

CAS: 201612-55-7

Ref. TM-T35683

Produktinformation

• Name: 2-deoxy-D-Glucose-13C6
• Synonyme: 2-Deoxy-D-[1-13C]Arabino-Hexose, 2-Deoxy-D-[1-13C]Glucose

Beschreibung

2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate.32-deoxy-D-Glucose (16 mM) induces apoptosis in SK-BR-3 cells, as well as inhibits the growth of 143B osteosarcoma cells cultured under hypoxic conditions when used at a concentration of 2 mg/ml.4,5

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 165.15
• Formel: C₅CH₁₂O₅