(Rac)-SAR131675

CAS: 1092539-44-0

Ref. TM-T3691

Produktinformation

• Name: (Rac)-SAR131675
• Synonyme: SAR131675
• CAS: 1092539-44-0

Beschreibung

(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is highly specific for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases. SAR131675 is a highly specific VEGFR-3-TK inhibitor with significant antitumoral and antimetastatic activities in vivo through inhibition of lymphangiogenesis and TAM invasion.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 358.39
• Formel: C₁₈H₂₂N₄O₄
• Reinheit: 99.1%
• Farbe/Form: Solid