MCC950

CAS: 210826-40-7

Ref. TM-T3701

Produktinformation

• Name: MCC950
• Synonyme: CP-456773
• CAS: 210826-40-7

Beschreibung

CP-456773 (MCC950 (CP-456773) and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and caspase 1 processing. MCC950 blocked canonical and noncanonical NLRP3 activation at nanomolar concentrations. MCC950 specifically inhibited activation of NLRP3 but not the AIM2, NLRC4 or NLRP1 inflammasomes. MCC950 reduced IL-1β production in vivo and attenuated the severity of experimental autoimmune encephalomyelitis (EAE), a disease model of multiple sclerosis.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 404.48
• Formel: C₂₀H₂₄N₂O₅S
• Reinheit: 98%
• Farbe/Form: Solid