BP-1-102

CAS: 1334493-07-0

Ref. TM-T3708

Produktinformation

• Name: BP-1-102
• CAS: 1334493-07-0

Beschreibung

BP-1-102 is an orally active, effective and specific STAT3 inhibitor. BP-1-102 binds Stat3 (Kd: 504 nM), then blocks Stat3-phosphotyrosine (pTyr) peptide interactions and Stat3 activation (4-6.8 μM), and selectively inhibits migration, survival, growth, and invasion of Stat3-dependent tumor cells. The BP-1-102-mediated inhibition of aberrantly active Stat3 in tumor cells suppresses the expression of c-Myc, Bcl-xL, Cyclin D1, Survivin, and VEGF.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 626.59
• Formel: C₂₉H₂₇F₅N₂O₆S
• Reinheit: 99.81%
• Farbe/Form: Solid