Mivebresib

CAS: 1445993-26-9

Ref. TM-T3712

Produktinformation

• Name: Mivebresib
• Synonyme: ABBV-075
• CAS: 1445993-26-9

Beschreibung

Mivebresib (ABBV-075), also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-containing protein) with potential antineoplastic activity. Upon administration, the bromodomain inhibitor ABBV-075 binds to the acetyl-lysine binding site in the BRD of certain BRD-containing protein(s), thereby preventing the interaction between those proteins and acetylated histones. This disrupts chromatin remodeling, prevents the expression of certain growth-promoting genes, and leads to an inhibition of cell growth in susceptible tumors. Also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 459.47
• Formel: C₂₂H₁₉F₂N₃O₄S
• Reinheit: 98.74%
• Farbe/Form: Solid