Polyphyllin I

CAS: 50773-41-6

Ref. TM-T3895

Produktinformation

• Name: Polyphyllin I
• Synonyme: Paris saponin Pa, Polyphillin D, Polyphyllin D, Chonglou Saponin I
• CAS: 50773-41-6

Beschreibung

Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D has an anti-angiogenic effect. Polyphyllin D has toxicity in human RBCs as well as its underlying mechanism for the hemolysis and eryptosis/erythroptosis. Polyphyllin D has strong anticancer activity, can overcome drug resistance in R-HepG2 cells and elicit programmed cell death via mitochondrial dysfunction.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 855.02
• Formel: C₄₄H₇₀O₁₆
• Reinheit: 99.36%
• Farbe/Form: Solid