Phellopterin

CAS: 2543-94-4

Ref. TM-T3927

Produktinformation

• Name: Phellopterin
• Synonyme: (5-Methoxy-8)-γ,γ-dimethylallyloxy(2′,3′,6,7-furanocoumarin), 4-Methoxy-9-[(3-methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one, 4-Methoxy-9-[(3-methyl-2-butenyl)oxy]-7H-furo[3,2-g]chromen-7-one, 5-Benzofuranacrylic acid, 6-hydroxy-4-methoxy-7-[(3-methyl-2-butenyl)oxy]-, δ-lactone, 7H-Furo(3,2-g)(1)benzopyran-7-one, 4-methoxy-9-((3-methyl-2-butenyl)oxy)-, 7H-furo[3,2-g][1]benzopyran-7-one, 4-methoxy-9-[(3-methyl-2-buten-1-yl)oxy]-, NSC 152469
• CAS: 2543-94-4

Beschreibung

Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro. Phellopterin shows a cytotoxic effect on RAW264.7 cell at the concentration from 40 to 400 μM. Phellopterin reduce TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 300.31
• Formel: C₁₇H₁₆O₅
• Reinheit: 99.99%
• Farbe/Form: Solid
• InChl: InChI=1S/C17H16O5/c1-10(2)6-8-21-17-15-12(7-9-20-15)14(19-3)11-4-5-13(18)22-16(11)17/h4-7,9H,8H2,1-3H3
• InChI Key: InChIKey=BMLZFLQMBMYVHG-UHFFFAOYSA-N
• SMILES: COc1c2ccoc2c(OCC=C(C)C)c2oc(=O)ccc12