Su1498

CAS: 168835-82-3

Ref. TM-T3980

Produktinformation

• Name: Su1498
• Synonyme: Tyrphostin SU 1498, AG 1498, 2-Propenamide,2-cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-, (E)-, Ag 1498, Su 1498, Tyrphostin SU 1498
• CAS: 168835-82-3

Beschreibung

Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 390.52
• Formel: C₂₅H₃₀N₂O₂
• Reinheit: 99.54%
• Farbe/Form: Solid