Flavokawain A

CAS: 3420-72-2

Ref. TM-T3S0737

Produktinformation

• Name: Flavokawain A
• Synonyme: Flavokavain A, (2E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one, 1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one, 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-, 2′-Hydroxy-4,4′,6′-trimethoxychalcone, 4-Methoxybenzylidene(4,6-dimethoxy-2-hydroxyacetophenone), Chalcone, 2′-hydroxy-4,4′,6′-trimethoxy-, NSC 37445
• CAS: 3420-72-2

Beschreibung

NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significantly reduce the expression of CDK1-inhibitory kinases, Myt1 and Wee1, and cause cyclin B1 protein accumulation leading to CDK1 activation in T24 cells. 3. Flavokawain A (Flavokavain A) may exert anti-inflammatory responses by suppressing LPS-induced expression of pro-inflammatory mediators via blockage of NF-κB-AP-1-JNK/p38 MAPK signaling pathways in the murine macrophages.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 314.33
• Formel: C₁₈H₁₈O₅
• Reinheit: 99.72%
• Farbe/Form: Solid