RORγt Inverse agonist 10

CAS: 2413986-35-1

Ref. TM-T40043

Produktinformation

• Name: RORγt Inverse agonist 10
• Marke: Targetmol
• Beschreibung: RORγt Inverse agonist 10 is a highly potent, orally bioavailable compound that acts as an antagonist for the retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt). With an IC50 of 51 nM, it effectively inhibits RORγt activity, a key transcription factor regulating genes linked to psoriasis pathogenesis, including [IL-17A], [IL-22], and [IL-23R].

Chemische Eigenschaften

• Molekulargewicht: 572.512
• Formel: C₂₅H₂₆F₆N₆O₃
• Farbe/Form: Solid