Thiocolchicine

CAS: 2730-71-4

Ref. TM-T41248

Produktinformation

• Name: Thiocolchicine
• Synonyme: 10-Demethoxy-10-(methylthio)colchicine, 10-Demethoxy-10-methylthiocolchicine, Acetamide, N-(5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo(a)heptalen-7-yl)-, Acetamide, N-(5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo(a)heptalen-7-yl)-, (S)-, Acetamide, N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-, Benzo[a]heptalene, acetamide deriv., Colchicine, 10-demethoxy-10-(methylthio)-, Colchicine, 10-thio-, Colchicine, thio-, N-[(7S)-1,2,3-trimethoxy-10-(methylsulfanyl)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide, N-[(7S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide, Nsc 186301, Sml 0954, Thiocholchicine
• CAS: 2730-71-4

Beschreibung

Thiocolchicine is an effective inhibitor of tubulin polymerization with an IC50 of 2.5 µM and a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 415.5
• Formel: C₂₂H₂₅NO₅S
• Reinheit: 98%
• Farbe/Form: Odour Solid