Aftin-4

CAS: 866893-90-5

Ref. TM-T4364

Produktinformation

• Name: Aftin-4
• Synonyme: Aftin 4, Aftin4
• CAS: 866893-90-5

Beschreibung

Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor. Aftin-4(Aftin4) increased Aβ-1-42, but not Aβ-1-40 in mouse hipppocampus, accompanied by learning deficits and mitochondrial ultrastructural changes similar to those found in the brains of patients with AD. Aftin-4(Aftin4) can thus be used to induce a rapid, acute Alzheimer's disease-like toxicity in the rodent brain.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 368.48
• Formel: C₂₀H₂₈N₆O
• Reinheit: 99.03%
• Farbe/Form: Solid