Olodanrigan

CAS: 1316755-16-4

Ref. TM-T4431

Produktinformation

• Name: Olodanrigan
• Synonyme: PD-126055, EMA401
• CAS: 1316755-16-4

Beschreibung

Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. EMA401 blocks p38, p42/p44 mitogen-activated protein kinase (MAPK) activation, neurite outgrowth in adult rat DRG neurons, and sensitization of adult rat and human DRG neurons induced by AngII. It inhibits capsaicin responses in cultured hDRG neurons.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 507.58
• Formel: C₃₂H₂₉NO₅
• Reinheit: 94.13%
• Farbe/Form: Solid