Dehydrocorydaline

CAS: 30045-16-0

Ref. TM-T5S2358

Produktinformation

• Name: Dehydrocorydaline
• Synonyme: Dehydrocorydalin, 13-Methylpalmatine, 13-Methylpalmatine, 2,3,9,10-Tetramethoxy-13-Methyl-5,6-Dihydroisoquino[3,2-A]Isoquinolinium, 2,3,9,10-Tetramethoxy-13-Methyl-5,6-Dihydroisoquino[3,2-A]Isoquinolinium Chloride, 2,3,9,10-Tetramethoxy-13-methyl-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium, 5,6-Dihydro-2,3,9,10-tetramethoxy-13-methyldibenzo[a,g]quinolizinium, 7,8,13,13a-Tetradehydro-2,3,9,10-tetramethoxy-13-methylberbinium, Berbinium, 7,8,13,13a-tetradehydro-2,3,9,10-tetramethoxy-13-methyl-, Brn 1556798, Corydaline, dehydro-, Dehydrocorydalin, Dibenzo(a,g)quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-13-methyl- (9CI), Dibenzo[a,g]quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-13-methyl-
• CAS: 30045-16-0

Beschreibung

1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. 3. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914 ug/mL). 4. Dehydrocorydaline has anti-inflammatory and antinociceptive effects. 5. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 366.43
• Formel: C₂₂H₂₄NO₄
• Reinheit: 98.36%
• Farbe/Form: Solid