GSK-1482160

CAS: 1001389-72-5

Ref. TM-T61025

Produktinformation

• Name: GSK-1482160
• CAS: 1001389-72-5

Beschreibung

GSK-1482160 is a CNS-penetrant negative allosteric modulator of P2X7 receptor with oral activity. The P2X7 receptor is involved in the production of pro-inflammatory cytokines by central and peripheral immune cells, so GSK-1482160 has the potential to study inflammatory diseases. GSK-1482160 shows excellent in vitro potency (in functional and electrophysiological assays at recombinant and naive P2X7 receptors across multiple species including humans) and cross-target selectivity.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 334.72
• Formel: C₁₄H₁₄ClF₃N₂O₂
• Reinheit: 99.87%
• Farbe/Form: Solid