Tipifarnib

CAS: 192185-72-1

Ref. TM-T6271

Produktinformation

• Name: Tipifarnib
• Synonyme: R115777, Zarnestra, IND 58359, (R)-(+)-R 115777, (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone, 2(1H)-Quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-, 6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one, Tipifarnib Zarnestra, Zarnestra
• CAS: 192185-72-1

Beschreibung

Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, this agent prevents the activation of Ras oncogenes, inhibits cell growth, induces apoptosis, and inhibits angiogenesis.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 489.4
• Formel: C₂₇H₂₂Cl₂N₄O
• Reinheit: 99.22%
• Farbe/Form: Off-White To Pale Beige Solid