Halobetasol propionate

CAS: 66852-54-8

Ref. TM-T6529

Produktinformation

• Name: Halobetasol propionate
• Synonyme: Halobetasol Propionate, Ulobetasol propionate, BMY-30056, CGP-14458, (6α,11β,16β)-21-Chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione, Bmy 30056, Cgp 14458, Halobetasol propionate, Miracorten, Ulobetasol propionate, Ultravate
• CAS: 66852-54-8

Beschreibung

Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses across cell membranes to interact with cytoplasmic corticosteroid receptors located in both the dermal and intradermal cells, thereby activating gene expression of anti-inflammatory proteins mediated via corticosteroid receptor response element. Specifically, this agent induces phospholipase A2 inhibitory proteins, which inhibit the release of arachidonic acid, thereby inhibiting the biosynthesis of potent mediators of inflammation, such as prostaglandins and leukotrienes. As a result, halobetasol reduces edema, erythema, and pruritus through its cutaneous effects on vascular dilation and permeability.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 484.96
• Formel: C₂₅H₃₁ClF₂O₅
• Reinheit: 99.85%
• Farbe/Form: Distributed As 0 05% Ointment