Epoxomicin

CAS: 134381-21-8

Ref. TM-T6830

Produktinformation

• Name: Epoxomicin
• Synonyme: BU-4061T, BU-4061T,Aids010837, (2R)-2-[Acetyl-(N-Methyl-L-Isoleucyl)-L-Isoleucyl-L-Threonyl-L-Leucyl]-2-Methyloxirane, <span class="text-smallcaps">L</smallcap>-Threoninamide, N-acetyl-N-methyl-<smallcap>L</smallcap>-isoleucyl-<smallcap>L</span>-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-, <span class="text-smallcaps">L</smallcap>-Threoninamide, N-acetyl-N-methyl-<smallcap>L</smallcap>-isoleucyl-<smallcap>L</span>-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-, Bu-4061T, Epoxomicin, Synthetic, N-Acetyl-N-Methyl-L-Isoleucyl-L-Isoleucyl-N-[(1S)-3-Methyl-1-[[(2R)-2-Methyloxiranyl]Carbonyl]Butyl]-L-Threoninamide, N-Acetyl-N-methyl-<span class="text-smallcaps">L</smallcap>-isoleucyl-<smallcap>L</smallcap>-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-<smallcap>L</span>-threoninamide, N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-L-threonyl-N-{2-[(2R)-2-methyloxiran-2-yl]-2-oxoethyl}-L-leucinamide, N-acetyl-N-methyl-L-isoleucyl-N-{(2S,3R)-3-hydroxy-2-[(3-methyl-1-{[(2R)-2-methyloxiran-2-yl]carbonyl}butyl)amino]butanoyl}-L-isoleucinamide
• CAS: 134381-21-8

Beschreibung

Epoxomicin (BU-4061T,Aids010837) is a selective proteasome inhibitor with anti-inflammatory activity, inhibits primarily the CH-L activity of the 20S proteasome, while T-L and PGPH catalytic activities are also inhibited at 100- and 1000-fold reduced rate.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 554.72
• Formel: C₂₈H₅₀N₄O₇
• Reinheit: 99.91%
• Farbe/Form: White To Off-White Solid