Linarin

CAS: 480-36-4

Ref. TM-T6S0653

Produktinformation

• Name: Linarin
• Synonyme: Buddleoflavonoloside, Buddleoside, Acacetin-7-O-rutinoside, Acaciin, Linarine, 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-, 5-Hydroxy-4′-methoxyflavone-7-O-rutinoside, 5-hydroxy-2-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside, 7-[[6-O-(6-Deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one, Acacetin 7-O-rutinoside, Acacetin 7-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→6)-β-<smallcap>D</span>-glucopyranoside, Acacetin-7-O-(6′′-O-rhamnose)-β-<span class="text-smallcaps">D</span>-glucoside, Acacetin-7-O-β-<span class="text-smallcaps">D</span>-rutinoside, Acaciin, Buddleoflavonoloside, Buddleoside, Linarigenin glycoside, Linarine
• CAS: 480-36-4

Beschreibung

1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediated apoptotic pathways. 3. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. 4. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 592.55
• Formel: C₂₈H₃₂O₁₄
• Reinheit: 97.81%
• Farbe/Form: White To Off White Powder