NX-2127

CAS: 2416131-46-7

Ref. TM-T73463

Produktinformation

• Name: NX-2127
• Synonyme: NX2127, NX 2127

Beschreibung

NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferative activity and inhibits the proliferation of BTKC481S mutant TMD8 cells.NX-2127 potently catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) at 25 nM and 54 nM, respectively. NX-2127 is associated with the immune system, stimulating T cell activation and increasing IL-2 production in primary human T cells.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 719.83
• Formel: C₃₉H₄₅N₉O₅
• Reinheit: 98.11%
• Farbe/Form: Solid