Tepoxalin

CAS: 103475-41-8

Ref. TM-T7724

Produktinformation

• Name: Tepoxalin
• Synonyme: RWJ-20485, RWJ20485, ORF20485, ORF-20485, RWJ 20485, ORF 20485, 1H-Pyrazole-3-propanamide, 5-(4-chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-, 3-(5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-pyrazolyl)-N-hydroxy-N-methylpropanamide, 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl]-N-hydroxy-N-methylpropanamide, 5-(4-Chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-1H-pyrazole-3-propanamide, 5-(p-Chlorophenyl)-1-(p-methoxyphenyl)-N-methylpyrazole-3-propionohydroxamic acid, Orf 20485, Rwj 20485, Tepoxalin [USAN:INN], Tepoxalina, Tepoxalina [Spanish], Tepoxaline, Tepoxaline [French], Tepoxalinum, Tepoxalinum [Latin], Unii-Tz4Ox61974, Zubrin
• CAS: 103475-41-8

Beschreibung

Tepoxalin (RWJ 20485) is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis. Tepoxalin inhibits COX-1, COX-2, and 5-LOX. Tepoxalin is a potent inhibitor of sheep seminal vesicle cyclooxygenase (COX) (IC50 = 4.6 microM), rat basophilic leukemia cell (RBL-1) lysate COX (IC50 = 2.85 microM) and COX from intact RBL-1 cells (IC50 = 4.2 microM).

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 385.84
• Formel: C₂₀H₂₀ClN₃O₃
• Reinheit: 99.03%
• Farbe/Form: Solid