MAO A/HSP90-IN-1

CAS: 2927489-95-8

Ref. TM-T79486

Produktinformation

• Name: MAO A/HSP90-IN-1

Beschreibung

MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of 1.77 μM in glioblastoma (GBM) GL26 cells and 0.019 μM against HSP90α. This compound impairs the activities of MAO A, disrupts HSP90 binding, and downregulates both HER2 and phospho-Akt expressions, thereby inhibiting GBM growth. Additionally, it diminishes PD-L1 expression, thereby thwarting T cell activation and potential tumor immune evasion. MAO A/HSP90-IN-1 (4-b) is valuable for research into brain tumor-related diseases [1].

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 444.95
• Formel: C₂₄H₂₉ClN₂O₄
• Reinheit: 98%