1-Arachidonoyl Glycerol

CAS: 35474-99-8

Ref. TM-T84599

Produktinformation

• Name: 1-Arachidonoyl Glycerol
• Synonyme: 1-AG, (all-Z)-(±)-2,3-Dihydroxypropyl 5,8,11,14-eicosatetraenoate, 1-Arachidonoylglycerol, 1-Arachidonylglycerol, 1-Monoarachidin, 1-Monoarachidonoyl-rac-glycerol, 5,8,11,14-Eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (all-Z)-, 5,8,11,14-eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (5Z,8Z,11Z,14Z)-

Beschreibung

2-Arachidonoylglycerol (2-AG) is identified as a more potent endogenous cannabinoid ligand compared to its analogue, 1-Arachidonoylglycerol (1-AG), exhibiting 10 to 100 times the ligand binding affinity and agonist activity at the CB1 receptor, thus making it a natural ligand. However, 2-AG's chemical instability leads to rapid isomerization to 1-AG (also referred to as 1(3)-AG) both in vitro and in vivo. This isomerization process, where 1-AG becomes a frequent contaminant in synthetic 1-AG preparations, significantly decreases their cannabinergic potency. Furthermore, 1-AG is characterized as a weak CB1 receptor agonist with potential for other pharmacological effects.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 378.6
• Formel: C₂₃H₃₈O₄
• Farbe/Form: Liquid