GHK-Cu acetate

CAS: 300801-03-0

Ref. TM-T85063

Produktinformation

• Name: GHK-Cu acetate
• Synonyme: Gly-His-Lys-Cu(II), Copper tripeptide acetate
• Marke: Targetmol
• Beschreibung: GHK-Cu acetate, a complex of the tripeptide Gly-His-Lys and a copper(II) ion, exhibits wound healing and anti-inflammatory properties. It enhances fibroblast proliferation, collagen production, and the release of pro-matrix metalloproteinase-2 (MMP-2) and glycosaminoglycans (GAGs), while also increasing decorin expression in rat wound tissue. Furthermore, at a concentration of 10 µM, it reduces levels of reactive oxygen species (ROS), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) in LPS-stimulated RAW 264.7 cells. Additionally, GHK-Cu at 10 µg/g mitigates LPS-induced reductions in lung superoxide dismutase (SOD) activity and glutathione (GSH) levels, decreases the accumulation of cells and total protein in bronchoalveolar lavage fluid (BALF), and thus, attenuates acute lung injury in mice.

Chemische Eigenschaften

• Molekulargewicht: 462
• Formel: C₁₄H₂₂CuN₆O₄C₂H₄O₂
• Farbe/Form: Solid