Gonadorelin acetate

CAS: 34973-08-5

Ref. TM-T85273

Produktinformation

• Name: Gonadorelin acetate
• Synonyme: Gonadelin Acetate, Luteinizing hormone-releasing factor (pig), acetate (salt), Cystorelin, Fertiline, Luprolite acetate, Lutrelef, Lutrepulse, Synthetic luteinizing hormone-releasing factor acetate, Luteinizing hormone-releasing factor (swine), acetate (salt), 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-L-prolylglycinamide acetate (1:1)

Beschreibung

Gonadorelin, a gonadotropin-releasing hormone receptor (GNRHR; Ki= 13 nM in CHO cells expressing the human receptor) agonist and tropic hormone, effectively stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from rat anterior pituitary cultures at 0.1 μg doses. Additionally, it triggers LH release from bovine anterior pituitary cultures at a 1 μM concentration. In vivo, gonadorelin induces ovulation in rats pretreated with fluphenazine (ED50= 610.3 ng/kg). Gonadorelin-based formulations are utilized as diagnostic tools to evaluate pituitary gland function.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 1242.363
• Formel: C₅₇H₇₉N₁₇O₁₅
• Farbe/Form: Solid