EGFR/HER2-IN-11

CAS: 1346176-20-2

Ref. TM-T86352

Produktinformation

• Name: EGFR/HER2-IN-11
• Marke: Targetmol
• Beschreibung: EGFR/HER2-IN-11 (compound 20), an orally active dual inhibitor targeting human epidermal growth factor receptor 2 (HER2) and epidermal growth factor receptor (EGFR), demonstrates IC50 values of 7.7 nM and 22 nM, respectively. This compound shows strong antitumor efficacy, specifically inhibiting the proliferation of BT-474 cancer cells with a GI50 of 601 nM [1].

Chemische Eigenschaften

• Molekulargewicht: 491.89
• Formel: C₂₃H₂₁ClF₃N₅O₂