BI-0115

CAS: 4929-23-1

Ref. TM-T9108

Produktinformation

• Name: BI-0115
• CAS: 4929-23-1

Beschreibung

BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. It binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain. The structure of LOX-1 bound to BI-0115 shows that inter-ligand interactions at the receptor interfaces are key to the formation of the receptor tetramer thereby blocking oxLDL binding.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 287.74
• Formel: C₁₅H₁₄ClN₃O
• Reinheit: 99.69%
• Farbe/Form: Solid