AICDA Protein, Mouse, Recombinant (His & Myc)

Ref. TM-TMPH-02908

Produktinformation

• Name: AICDA Protein, Mouse, Recombinant (His & Myc)
• Synonyme: Single-stranded DNA cytosine deaminase, Cytidine aminohydrolase, Activation-induced cytidine deaminase, AID

Beschreibung

Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 31.5 kDa (predicted)
• Farbe/Form: Solid