ACVR2A Protein, Human, Recombinant (hFc & His)

Ref. TM-TMPJ-00315

Produktinformation

• Name: ACVR2A Protein, Human, Recombinant (hFc & His)
• Synonyme: ACTR-IIA, Activin Receptor Type IIA, ACTRIIA, Activin Receptor Type-2A, ACVR2, ACVR2A

Beschreibung

Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 60KDa&40KDa (reducing condition)
• Farbe/Form: Solid