AMIGO2 Protein, Human, Recombinant (hFc)

Ref. TM-TMPJ-00320

Produktinformation

• Name: AMIGO2 Protein, Human, Recombinant (hFc)
• Synonyme: DEGA, AMIGO-2, AMIGO2, ALI1, Alivin-1, Amphoterin-Induced Protein 2, Differentially Expressed in Gastric Adenocarcinomas

Beschreibung

Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain, and may be required for tumorigenesis of a subset of gastric adenocarcinomas.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 93 KDa (reducing condition)
• Farbe/Form: Solid