OGG1 Protein, Human, Recombinant

Ref. TM-TMPJ-00457

Produktinformation

• Name: OGG1 Protein, Human, Recombinant
• Synonyme: OGH1, N-Glycosylase/DNA Lyase, DNA-(Apurinic or Apyrimidinic Site) Lyase, AP Lyase, MMH, 8-Oxoguanine DNA Glycosylase, MUTM, OGG1

Beschreibung

Human N-Glycosylase/DNA Lyase(OOG1) is a DNA repair enzyme, which belongs to the type-1 OGG1 family. OOG1 incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damage DNA. It has a β-lyase activity that nicks DNA 3’ to the lesion. OOG1 together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. The OGG1 gene mutations may be caused Renal cell carcinoma.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 38 KDa (reducing condition)
• Farbe/Form: Solid