![discount label](https://static.cymitquimica.com/public/img/discount.png)
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His)
Ref. TM-TMPJ-00655
1mg | 1.585,00 € | ||
10µg | 70,00 € | ||
50µg | 185,00 € | ||
500µg | 1.098,00 € |
Produktinformation
- TRAIL-R1, TNFRSF10A, cytotoxic TRAIL receptor, APO2, CD261 antigen, TRAILR1, DR4, TNF-related apoptosis-inducing ligand receptor 1, CD261
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily. TNFRSF10A / DR4 is widely expressed and high levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells. APO2 / TNFRSF10A is receptor for the cytotoxic ligand TNFSF10 / TRAIL. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF1/TRAIL), and thus transduces cell death signal and induces cell apoptosis. TRAIL R1 can promote the activation of NF-kappa-B. TRAIL R1/CD261/TNFRSF1A induces apoptosis of many transformed cell lines but not of normal tissues, even though its death domain-containing receptor, DR4, is expressed on both cell types.
Chemische Eigenschaften
Technische Anfrage zu: TM-TMPJ-00655 TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His)
Wenn Sie ein Angebot anfordern oder eine Bestellung aufgeben möchten, legen Sie stattdessen die gewünschten Produkte in Ihren Warenkorb und fordern Sie dann ein Angebot oder eine Bestellung an aus dem Warenkorb. Es ist schneller, billiger und Sie können von den verfügbaren Rabatten und anderen Vorteilen profitieren.