MPZ Protein, Human, Recombinant (His)

Ref. TM-TMPJ-00913

Produktinformation

• Name: MPZ Protein, Human, Recombinant (His)
• Synonyme: Myelin Peripheral Protein, Myelin Protein P0, MPZ, Myelin Protein Zero, MPP

Beschreibung

Myelin Protein P0 (MPZ) is a single-pass type I membrane glycoprotein which belongs to the myelin P0 protein family. MPZ contains one Ig-like V-type (immunoglobulin-like) domain, absent in the central nervous system. MPZ is a major component of the myelin sheath in peripheral nerves. It is postulated that MPZ is a structural element in the formation and stabilisation of peripheral nerve myelin, holding its characteristic coil structure together by the interaction of its positively-charged domain with acidic lipids in the cytoplasmic face of the opposed bilayer, and by interaction between hydrophobic globular of adjacent extracellular domains. Defects in MPZ associated with Charcot-Marie-Tooth disease and Dejerine-Sottas disease.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 14-17 KDa (reducing condition)
• Farbe/Form: Solid