HABP2 Protein, Human, Recombinant (His)

Ref. TM-TMPJ-01116

Produktinformation

• Name: HABP2 Protein, Human, Recombinant (His)
• Synonyme: Factor seven-activating protease, Factor VII-activating protease, Plasma hyaluronan-binding protein, Hepatocyte growth factor activator-like protein, Hyaluronan-binding protein 2

Beschreibung

Hyaluronan-binding protein 2(HABP2) is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' , but not the gamma-chain of fibrinogen. As a result of this, it does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator to the active two chain form, activates coagulation factor VII.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 35-40 KDa (reducing condition)
• Farbe/Form: Solid