TDGF1/Cripto Protein, Human, Recombinant (His)

Ref. TM-TMPK-00073

Produktinformation

• Name: TDGF1/Cripto Protein, Human, Recombinant (His)
• Synonyme: TDGF1, Cripto, CR, CRGF

Beschreibung

TDGF1 (CRIPTO) is a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF/CFC) gene family and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, and left-right axis development in model organisms. Cripto-1 is enriched in a subpopulation of embryonal, melanoma, prostate, and pancreatic cancer cells that possess stem-like characteristics. Therefore, Cripto-1 may play a role during developmental EMT, and it may also be involved in the reprogramming of differentiated tumor cells into cancer stem cells through the induction of an EMT program.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 16.92 kDa (predicted). Due to glycosylation, the protein migrates to 23-30 kDa based on Tris-Bis PAGE result.
• Farbe/Form: Solid