CTLA-4 Protein, Human, Recombinant (His & Avi), Biotinylated

Ref. TM-TMPK-00112

Produktinformation

• Name: CTLA-4 Protein, Human, Recombinant (His & Avi), Biotinylated
• Synonyme: IDDM12, ICOS, CD152, GRD4, CTLA4, CELIAC3, GSE, ALPS5

Beschreibung

CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation - a phenomenon which is particularly notable in cancers. It acts as an "off" switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 16.3 kDa (predicted). Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.
• Farbe/Form: Solid