FOLR1 Protein, Human, Recombinant (His & Avi)

Ref. TM-TMPK-00150

Produktinformation

• Name: FOLR1 Protein, Human, Recombinant (His & Avi)
• Synonyme: Folate receptor 1, Folbp1, Folate receptor alpha, FR-alpha, FR alpha, FOLR, Folate receptor α, FR-α, FOLR1, FR α, FBP, KB cells FBP, Fbp1, MOv18

Beschreibung

Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 27.5 kDa (predicted). Due to glycosylation, the protein migrates to 38-45 kDa based on Tris-Bis PAGE result.
• Farbe/Form: Solid