B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)

Ref. TM-TMPK-00314

Produktinformation

• Name: B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)
• Synonyme: B7-H3, PSEC0249, PRO352, 4Ig-B7-H3, B7 homolog 3, UNQ309, CD276

Beschreibung

B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig-B7-H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 49.5 kDa and the accession number is Q5ZPR3-1.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 49.5 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
• Farbe/Form: Solid