MERTK/Mer Protein, Human, Recombinant (His)

Ref. TM-TMPK-00417

Produktinformation

• Name: MERTK/Mer Protein, Human, Recombinant (His)
• Synonyme: Tyro12, MGC133349, c-mer, MERTK, c-Eyk, RP38, MER

Beschreibung

MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans. MERTK/Mer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.73 kDa and the accession number is Q12866-1.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 53.73 kDa (predicted). Due to glycosylation, the protein migrates to 95-115 kDa based on Tris-Bis PAGE result.
• Farbe/Form: Solid