EPHB2 Protein, Cynomolgus, Recombinant (His)

Ref. TM-TMPK-00563

Produktinformation

• Name: EPHB2 Protein, Cynomolgus, Recombinant (His)
• Synonyme: DRT, Nuk, Sek3, TYRO5, EPHT3, HEK5, EphB2, Qek2, PCBC, EPHT3MGC87492, EK5, Cek5, ERK, CAPB

Beschreibung

EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2 is epigenetically overexpressed in hypoxia, a condition highly prevalent in malignancy. Furthermore, HIF-2α is required for EPHB2 stabilization by hypoxia.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 59.09 kDa (predicted). Due to glycosylation, the protein migrates to 65-75 kDa based on Tris-Bis PAGE result.
• Farbe/Form: Solid