LILRB4/CD85k/ILT3 Domain 1 Protein, Human, Recombinant (His & Avi)

Ref. TM-TMPK-00605

Produktinformation

• Name: LILRB4/CD85k/ILT3 Domain 1 Protein, Human, Recombinant (His & Avi)
• Synonyme: LILRB4, ILT-3, HM18, LIR5, CD85K, ILT3

Beschreibung

LILRB4,also known as CD85k and LIR-5, ILT-3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT-3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k/ILT3 Domain 1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 14.26 kDa and the accession number is AAH26309.1.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 14.26 kDa (predicted). Due to glycosylation, the protein migrates to 14.5-20 kDa based on Tris-Bis PAGE result.
• Farbe/Form: Solid