PRNP/Prion Protein, Mouse, Recombinant (hFc)

Ref. TM-TMPK-00775

Produktinformation

• Name: PRNP/Prion Protein, Mouse, Recombinant (hFc)
• Synonyme: Major prion protein, PrP, ALTPRP, PRIP, PRNP

Beschreibung

Prion protein gene (PRNP) variants determine the susceptibility of humans, sheep and mice to prion diseases, whereas polymorphisms in the open reading frame (ORF) of bovine PRNP seem to be unrelated to the incidence of bovine spongiform encephalopathy (BSE). According to the latest reports, the genetic susceptibility of cattle to BSE is associated with polymorphisms ofthe regulatory region of the PRNP gene and the level ofits expression.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 49.6 kDa (predicted). Due to glycosylation, the protein migrates to 60-68 kDa based on Tris-Bis PAGE result.
• Farbe/Form: Solid